The Dead Eyes killer lurks in the backyard of the FBI's famed Behavioral Analysis Unit. His brutal murders, unlike any others previously encountered, confound the local task force, despite the gifted skills of Special Agent Karen Vail, the first female ever promoted to the profiling unit. But along with her keen insight, she brings considerable personal and professional baggage both of which threaten to derail their investigation.

When a powerful firebomb destroys part of an art gallery in an exclusive London district, FBI Profiler Karen Vail is dispatched to England to work with Scotland Yard. But Vail soon discovers that at the heart of the bombing lies a 440-year-old manuscript that holds clues to England's past -- with content is so explosive that a group of political radicals is bent on destroying it at all costs.

Vail's boyfriend, Detective Robby Hernandez, has seemingly disappeared into the dense air of a Napa Valley evening. There are no clues to his whereabouts, other than a blood stain--and potential connections to a serial killer operating in the wine country.